LC-MS(MS) is just HPLC with a fancy detector. Right?

That's the way it should be, but in reality it isn't. Getting to the stage of the instrument running reliably and obtaining any kind of meaningful results can be a long and very frustrating road.

Although an incredibly useful technique for certain applications, it can be brutally unforgiving to the in-experienced, with the most trival of errors resulting in a instrument stripdown with depressing regularity. It also has some significant differences from GC-MS, noteably huge limitations on dealing with complete unknowns. It is also NOT a universal detector and there are many types of molecules it simply cannot be used with.

As a hyphenated technique, you need to develop expertise in both HPLC and MS. There is simply no short-cutting this process and the steep learning curve demands time and commitment from the organisation and staff operating the instrument. However, Fox can help you develop an effective,  strong and lasting expertise in LC-MS in the shortest possible time, whatever your area of analysis. Helping you avoid all the mistakes and pitfalls that we've already made during our extensive practical experience.

This includes helping you establish the necessary specialist approaches to method development that ensure you obtain optimal results and performance from your LC-MS.

Get in touch with us at Fox, we'd be delighted to hear from you and talk through your hurdles and requirements.